Friday, November 1, 2013

Low-frequency rTMS prevents chronic epileptic seizure

Low-frequency rTMS prevents chronic epileptic seizure


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PUBLIC RELEASE DATE:

31-Oct-2013



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Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research





Although increasing evidence indicates that low-frequency repetitive transcranial magnetic stimulation (rTMS), an emerging technology for neural regulation, has antiepileptic effects, the mechanism remains unclear. Prof. Xiaoming Wang and team from the Affiliated Hospital of North Sichuan Medical College, China investigated the influence of low-frequency repetitive transcranial magnetic simulation on changes in several nonlinear dynamic electroencephalographic parameters in rats with chronic epilepsy and explored the mechanism underlying repetitive transcranial magnetic simulation-induced antiepileptic effects. In their study, an epilepsy model was established using lithium-pilocarpine intraperitoneal injection into adult Sprague-Dawley rats, which were then treated with repetitive transcranial magnetic simulation for 7 consecutive days. Nonlinear electroencephalographic parameters were obtained from the rats at 7, 14, and 28 days post-stimulation. Results showed significantly lower mean correlation-dimension and Kolmogorov-entropy values for stimulated rats than for non-stimulated rats. Low-frequency repetitive transcranial magnetic simulation has suppressive effects on electrical activity in epileptic rats, thus explaining its effectiveness in treating epilepsy. These findings were published in the Neural Regeneration Research (Vol. 8, No. 27, 2013).


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Article: " Low-frequency repetitive transcranial magnetic simulation prevents chronic epileptic seizure " by Yinxu Wang, Xiaoming Wang, Sha Ke, Juan Tan, Litian Hu, Yaodan Zhang, Wenjuan Cui (Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China)


Wang YX, Wang XM, Ke S, Tan J, Hu LT, Zhang YD, Cui WJ. Low-frequency repetitive transcranial magnetic simulation prevents chronic epileptic seizure. Neural Regen Res. 2013;8(27):2566-2572.


Contact:

Meng Zhao

eic@nrren.org

86-138-049-98773

Neural Regeneration Research

http://www.nrronline.org/

Full text: http://www.sjzsyj.org/CN/article/downloadArticleFile.do?attachType=PDF&id=730




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Low-frequency rTMS prevents chronic epileptic seizure


[ Back to EurekAlert! ]

PUBLIC RELEASE DATE:

31-Oct-2013



[


| E-mail

]


Share Share

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research





Although increasing evidence indicates that low-frequency repetitive transcranial magnetic stimulation (rTMS), an emerging technology for neural regulation, has antiepileptic effects, the mechanism remains unclear. Prof. Xiaoming Wang and team from the Affiliated Hospital of North Sichuan Medical College, China investigated the influence of low-frequency repetitive transcranial magnetic simulation on changes in several nonlinear dynamic electroencephalographic parameters in rats with chronic epilepsy and explored the mechanism underlying repetitive transcranial magnetic simulation-induced antiepileptic effects. In their study, an epilepsy model was established using lithium-pilocarpine intraperitoneal injection into adult Sprague-Dawley rats, which were then treated with repetitive transcranial magnetic simulation for 7 consecutive days. Nonlinear electroencephalographic parameters were obtained from the rats at 7, 14, and 28 days post-stimulation. Results showed significantly lower mean correlation-dimension and Kolmogorov-entropy values for stimulated rats than for non-stimulated rats. Low-frequency repetitive transcranial magnetic simulation has suppressive effects on electrical activity in epileptic rats, thus explaining its effectiveness in treating epilepsy. These findings were published in the Neural Regeneration Research (Vol. 8, No. 27, 2013).


###

Article: " Low-frequency repetitive transcranial magnetic simulation prevents chronic epileptic seizure " by Yinxu Wang, Xiaoming Wang, Sha Ke, Juan Tan, Litian Hu, Yaodan Zhang, Wenjuan Cui (Department of Neurology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China)


Wang YX, Wang XM, Ke S, Tan J, Hu LT, Zhang YD, Cui WJ. Low-frequency repetitive transcranial magnetic simulation prevents chronic epileptic seizure. Neural Regen Res. 2013;8(27):2566-2572.


Contact:

Meng Zhao

eic@nrren.org

86-138-049-98773

Neural Regeneration Research

http://www.nrronline.org/

Full text: http://www.sjzsyj.org/CN/article/downloadArticleFile.do?attachType=PDF&id=730




[ Back to EurekAlert! ]

[


| E-mail


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]

 


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.




Source: http://www.eurekalert.org/pub_releases/2013-10/nrr-lrp103113.php
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